PARP1 is upregulated in trastuzumab-resistant (TR) cells, and functions distinctive from parental cellsĪ The expression level of PARP1, and pADPr in TR cells and their counter parental cells was determined by western blotting. Data of three independent experiments are presented as mean ± SD, ns: not significant, *p < 0.05 **p < 0.005. (Right) Each scattered dot represents the tail moment of single cell. (Left) Representative images of the assay are shown. C Cells treated with trastuzumab (10 µg/ml) for the indicated time period were subjected to comet assays. B Whole-cell lysate (WCL) was prepared and immunoblotted for determining the expression level of γ-H2AX. The percentage of γ-H2AX-positive cells was determined by examining n > 150 cells per sample. (Left) Representative images are presented, and the scale bar is 10 µm. After fixation, cells were permeabilized with 0.5% Triton X-100 and stained for γ-H2AX (red) and counterstained with DAPI (blue). Thai-English-French: Volubilis Dictionary 1.TR cells sustains the functional DDR pathway to restore DSBs induced by trastuzumabĪ Cells were treated with trastuzumab (10 µg/ml) for the indicated periods. (n) anode, See also: positive electrode, Syn. (adv) confidently, See also: positively, Syn. Thai-English: NECTEC's Lexitron-2 Dictionary Try to have a positive attitude on everything. She shows a very positive attitude to her work. I've decided to be more positive and give it all I've got.ĭropped my abrupt contradiction and positive argumentation,Īnd put on the humble inquirer and doubter.

You are looking for ways to solve the problems that you can solve,Īnd you are letting go of the things over which you have no control. I am positive about his about his having finished. He gave a positive answer to my question. You arrange all this to influence positive future of Siam. Is that a positive ID? - She went to school with my son.Īnd I'm positive that if Uncle Conrad and Aunt. Forensics say a 100 percent positive id. ว่าเขาจะเป็นบวกเกี่ยวกับอะไร? 12 Angry Men (1957)Īs the disarmament talks here continue through closed sessions last night and on into this afternoon,Ī feeling of positive anticipation is shared by everyone in the press corps. assertively, emphatically, undoubtedly, absolutelyĮnglish-Thai: HOPE Dictionary

Positive syn